In addition to being a clinician, Prof. Frauke Alves has a long standing track record in basic research and preclinical evaluation of tumor therapies and diagnostic tools by applying molecular imaging techniques in oncology. She heads a research group in the Dept. of Hematology and Medical Oncology and Institute of Diagnostic and Radiology at the University Medicine Center, Goettingen, Germany. In addition, since 2008 she is leading a second research group at the Max-Planck-Institute for Experimental Medicine with the aim to translate basic knowledge into clinical practice. The focus of her interdisciplinary molecular imaging group is the investigation of mechanisms of tumor progression, angiogenesis and inflammation as well as the development of therapeutic approaches and diagnostic tools in nanomedicine and oncology. Orthotopic metastatic and transgenic tumor mouse models are applied in combination with non-invasive optical imaging techniques and nanoparticle based fluorescent probes in the near infrared range to evaluate the concept of novel tumor therapies e.g image guided surgery.