Dr. Grattoni obtained his Bachelor and Master Degree in Mechanical Engineering at the Politecnico of Torino, Turin, Italy focusing his studies on osmotic pressure of no-ideal solutions though nanoporous membranes. Dr. Grattoni obtained his Ph.D. degree in Biomedical Engineering at Politecnico of Torino while working in Dr. Mauro Ferrari’s team at the University of Texas Health Science Center at Houston. In this new context, he engaged in the study of transport phenomena in silicon nanofluidic devices for drug delivery. Since then he direct the nanochannel Delivery System (nDS) project focused on the development, and validation of nanochannel membranes for long-term administration of therapeutics from implantable capsules. His research is dedicated to experimental and phenomenological analysis in vitro and in vivo of concentration-driven transport in nanoconfinement developing experimental tools and mathematical models of the nanofluidic system. Additionally he engaged in the analysis of electrokinetic transport in nanochannels for the purpose of modulating the release of therapeutics from reservoirs. Finally, Dr. Grattoni’s team is developing novel microencapsulation for cell transplantation. Dr. Grattoni collaborates with the company NanoMedical Systems (NMS) Inc., Austin, TX, toward the translation of the nDS technology to the clinic. Currently he is serving as the Chairman of the Department of Nanomedicine at the Houston Methodist Research Institute. His team has received support from NASA, NIH, CASIS, Vivian Smith Foundation, Nancy Owens Memorial Foundation, as well as NanoMedical Systems, Inc.
Major Areas of Research
Nanomedicine, Nanofluidics, Drug Delivery, Silicon Technologies, Implantable Devices, Space Medicine, Cell Transplantation